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"Unpacking" Muscles

"Unpacking" Muscles

  • 4/8/2018 7:00:00 AM
  • View Count 54
Jessica Cardin, M.S.Skeletal muscle has a high degree of plasticity that allows the tissue to respond to environmental cues (exercise, disuse, starvation, etc.). The majority of research has focused on the building of muscle. However, atrophy has vast implications across many disease states (cancer cachexia, renal failure, COPD, and Type II Diabetes). The understanding of how atrophy occurs as an "unpacking" process of the muscle fiber is limited. Pioneering research is important as it...
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What Horses Can Tell Us About Humans

What Horses Can Tell Us About Humans

  • 3/26/2018 6:30:00 AM
  • View Count 104
Christine Latham, M.S.Currently, rodents are the most commonly used model for human aging, but because they have much shorter lifespans and many physical dissimilarities from humans, they may not be the best possible model for humans. So, what should we use if the time-honored rodent model is not the best option? Interestingly enough, horses may be able to fill the gap between easy-to-use mouse models and hard-to-control human studies. But why horses? Horses are an athletic species, they have th...
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Are MicroRNA's the Connection Between Exercise and Breast Cancer?

Are MicroRNA's the Connection Between Exercise and Breast Cancer?

  • 3/5/2018 6:30:00 AM
  • View Count 183
Chelsea Goodenough, HBScBreast cancer is the most common type of cancer that kills women world-wide [1]. Emerging out from under the emotional and financial burden of this disease is the united front of patients, families and researchers alike seeking to understand the complexity of this disease. With exercise's noted benefit to a 30-40% reduction in breast cancer risk, investigation into mechanisms that may be attributing to these findings have unveiled a frontrunner - microRNA. MicroRNA ar...
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Nutrition and Exercise: Timing is Everthing

Nutrition and Exercise: Timing is Everthing

  • 2/19/2018 6:30:00 AM
  • View Count 325
Tyler Grubic, M.S.Intense weight lifting and/or sprints, including acute single bouts, can promote exercise-induced stress responses, characterized by muscle damage and inflammation similar to stress associated with cardiovascular events and illnesses [10-12]. Decreased performance due to muscle soreness is not the direct result of inflammation, but rather a product of pain and mechanical receptor sensitivity to products of muscle breakdown, such as circulating chemicals and intramuscular protei...
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Think BIG, Start SMALL: MicroRNAs and Breast Cancer

Think BIG, Start SMALL: MicroRNAs and Breast Cancer

  • 12/4/2016 5:22:00 PM
  • View Count 1579
Chelsea Goodenough, B.S.The human body is capable of powerful things. When in prime condition, we are capable of adrenaline induced She-Hulk strength, and fighting the effect of zero gravity by walking on the moon. This, to most of us, is recognizable as disease, and is amongst us in the form of diabetes, heart disease, obesity, and chronic obstructive pulmonary disease (COPD) to name only a few. A disease that affects nearly 246,660 new people every year, is breast cancer, with an estimated 40,...
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Powering Skeletal Muscle Growth

Powering Skeletal Muscle Growth

  • 6/25/2014 3:16:00 AM
  • View Count 1378
Jacqueline I. Perticone, B.S.Loss of muscle mass with advancing age, disease or lifestyle has a profound influence on healthcare and society. Our laboratory uses hindlimb suspension in rodents to better understand loss of muscle mass occurring with disuse in an effort to design specific interventions that may be suitable to maintain muscle health and function in a number of populations. It is well-known that loss of muscle mass with reduced activity results from a slowdown in the muscle’s ...
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Don't Want to Lose Muscle Mass While Dieting? Take BCAAs!

  • 6/19/2014 2:30:00 AM
  • View Count 2589
Vincent C.W. Chen, B.S.When eating less to reduce weight, it is hard not to lose some muscle mass. During dieting, the body struggles to keep sufficient energy stores, and therefore, it will break down muscle proteins to satisfy energy needs. While the basic equation for muscle mass is rate of protein synthesis subtracted rate of protein breakdown, decrease in muscle size will be observed if muscle protein breakdown is not prevented while on a calorie-deficit diet.It has been well established th...
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Understanding mTOR: Great for Muscle, Bad for Cancer

Understanding mTOR: Great for Muscle, Bad for Cancer

  • 6/18/2014 9:02:00 AM
  • View Count 5613
Kevin Shimkus, B.S.In muscle research, we tend to pay a great deal of attention to a particular signaling protein called mTOR, a key regulatory protein that signals for cell growth through the creation of new proteins. Consider protein building similar to a race car. The larger the engine, the greater potential for speed. Similarly, the more mTOR protein present in any given cell, the greater potential for more protein construction. And just like the gas pedal fuels the engine, mTOR is a signali...
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Popeye's Secret is About to be Revealed

Popeye's Secret is About to be Revealed

  • 7/25/2013 5:24:00 AM
  • View Count 1342
Chang Woock Lee, B.A.          Do you remember Popeye the Sailor, the cartoon and animation character with massive forearms and a smoking pipe in his mouth? He usually shows a calm and gentle demeanor, but when necessary, especially to protect Olive Oyl, the love of his life, from his archrival Bluto, he suddenly turns into a hyperactive action hero with superhuman strength by eating his magic food, a can of spinach.      ...
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Should Women Do Resistance Exercise?

  • 7/18/2013 4:27:00 AM
  • View Count 5105
Vincent Chen, B.S When talking about resistance exercise, some people believe that women respond less than men in terms of muscle mass and strength gain, while others think that it may make women look bulky. Many women therefore tend to avoid doing resistance exercise. However, the benefits outweigh the possible drawback of bulkier appearance. Physical inactivity-induced muscle loss may reduce an individual's ability to resist impact and lower the basal metabolic rate (BMR) to an unheal...
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