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Muscle Atrophy Cures Found At The Supermarket

Muscle Atrophy Cures Found At The Supermarket

  • 5/28/2018 6:30:00 AM
  • View Count 315
Dylan Holly, M.Ed.Skeletal muscle is a complex tissue and while its primary job is to assist in movement, this is not its sole purpose. Muscle is also a major storehouse for energy in the form of amino acids and metabolic machinery responsible for much of our daily energy expenditure. The energy cost of muscle comes with a price. When subjected to an unloaded state such as bed-rest, immobilization, or microgravity, the muscle atrophies. In other words, the cross-sectional area diminishes and wit...
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New Pharmacological Interventions For Space And Disuse Atrophy

New Pharmacological Interventions For Space And Disuse Atrophy

  • 5/14/2018 5:30:00 AM
  • View Count 258
Patrick Ryan, M.S.Physical inactivity, whether due to sedentary lifestyle or bedrest while recovering from injury or illness, is a significant detriment to overall health. In the short term, reducing activity results in muscle atrophy: the loss of both muscle size and strength. This problem not only applies to athletes who may be forced to reduce activity due to an orthopedic injury, or adults living a sedentary lifestyle, but is also a huge concern in regards to manned spaceflight.In low Earth ...
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How to Stay Strong in Outer Space

How to Stay Strong in Outer Space

  • 4/30/2018 5:30:00 AM
  • View Count 1326
Dylan Holly, M.Ed.Skeletal muscle is a complex and dynamic tissue that can adapt to mechanical stress or lack thereof. Muscle is not only responsible for human movement in a three dimensional world but is also a major storehouse for amino acids and metabolic machinery. When subjected to an unloaded state typically seen in a bedrest, casted, or microgravity situation the muscle atrophies, or in other words wastes away. Along with this wasting comes a decrease in muscular strength and enduran...
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"Unpacking" Muscles

"Unpacking" Muscles

  • 4/8/2018 7:00:00 AM
  • View Count 338
Jessica Cardin, M.S.Skeletal muscle has a high degree of plasticity that allows the tissue to respond to environmental cues (exercise, disuse, starvation, etc.). The majority of research has focused on the building of muscle. However, atrophy has vast implications across many disease states (cancer cachexia, renal failure, COPD, and Type II Diabetes). The understanding of how atrophy occurs as an "unpacking" process of the muscle fiber is limited. Pioneering research is important as it...
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What Horses Can Tell Us About Humans

What Horses Can Tell Us About Humans

  • 3/26/2018 6:30:00 AM
  • View Count 394
Christine Latham, M.S.Currently, rodents are the most commonly used model for human aging, but because they have much shorter lifespans and many physical dissimilarities from humans, they may not be the best possible model for humans. So, what should we use if the time-honored rodent model is not the best option? Interestingly enough, horses may be able to fill the gap between easy-to-use mouse models and hard-to-control human studies. But why horses? Horses are an athletic species, they have th...
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Are MicroRNA's the Connection Between Exercise and Breast Cancer?

Are MicroRNA's the Connection Between Exercise and Breast Cancer?

  • 3/5/2018 6:30:00 AM
  • View Count 436
Chelsea Goodenough, HBScBreast cancer is the most common type of cancer that kills women world-wide [1]. Emerging out from under the emotional and financial burden of this disease is the united front of patients, families and researchers alike seeking to understand the complexity of this disease. With exercise's noted benefit to a 30-40% reduction in breast cancer risk, investigation into mechanisms that may be attributing to these findings have unveiled a frontrunner - microRNA. MicroRNA ar...
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Nutrition and Exercise: Timing is Everthing

Nutrition and Exercise: Timing is Everthing

  • 2/19/2018 6:30:00 AM
  • View Count 572
Tyler Grubic, M.S.Intense weight lifting and/or sprints, including acute single bouts, can promote exercise-induced stress responses, characterized by muscle damage and inflammation similar to stress associated with cardiovascular events and illnesses [10-12]. Decreased performance due to muscle soreness is not the direct result of inflammation, but rather a product of pain and mechanical receptor sensitivity to products of muscle breakdown, such as circulating chemicals and intramuscular protei...
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Think BIG, Start SMALL: MicroRNAs and Breast Cancer

Think BIG, Start SMALL: MicroRNAs and Breast Cancer

  • 12/4/2016 5:22:00 PM
  • View Count 2545
Chelsea Goodenough, B.S.The human body is capable of powerful things. When in prime condition, we are capable of adrenaline induced She-Hulk strength, and fighting the effect of zero gravity by walking on the moon. This, to most of us, is recognizable as disease, and is amongst us in the form of diabetes, heart disease, obesity, and chronic obstructive pulmonary disease (COPD) to name only a few. A disease that affects nearly 246,660 new people every year, is breast cancer, with an estimated 40,...
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Powering Skeletal Muscle Growth

Powering Skeletal Muscle Growth

  • 6/25/2014 3:16:00 AM
  • View Count 1697
Jacqueline I. Perticone, B.S.Loss of muscle mass with advancing age, disease or lifestyle has a profound influence on healthcare and society. Our laboratory uses hindlimb suspension in rodents to better understand loss of muscle mass occurring with disuse in an effort to design specific interventions that may be suitable to maintain muscle health and function in a number of populations. It is well-known that loss of muscle mass with reduced activity results from a slowdown in the muscle’s ...
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Don't Want to Lose Muscle Mass While Dieting? Take BCAAs!

  • 6/19/2014 2:30:00 AM
  • View Count 3080
Vincent C.W. Chen, B.S.When eating less to reduce weight, it is hard not to lose some muscle mass. During dieting, the body struggles to keep sufficient energy stores, and therefore, it will break down muscle proteins to satisfy energy needs. While the basic equation for muscle mass is rate of protein synthesis subtracted rate of protein breakdown, decrease in muscle size will be observed if muscle protein breakdown is not prevented while on a calorie-deficit diet.It has been well established th...
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